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Related Concept Videos

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...

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Related Experiment Video

Updated: Jun 24, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
07:49

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

Mortality in diastolic heart failure: an update.

Timothy P Fitzgibbons1, Theo E Meyer, Gerard P Aurigemma

  • 1Department of Medicine, University of Massachusetts Medical School, Worcester, USA.

Cardiology in Review
|April 16, 2009
PubMed
Summary

Diastolic heart failure (DHF), also known as heart failure with preserved ejection fraction, is increasingly prevalent and carries a high mortality risk comparable to systolic heart failure.

Related Experiment Videos

Last Updated: Jun 24, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
07:49

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

Area of Science:

  • Cardiology
  • Public Health

Background:

  • Heart failure affects millions, with diastolic heart failure (DHF) prevalence underestimated historically.
  • Contemporary studies reveal a rising prevalence of DHF in the community.
  • Increasing age, hypertension, obesity, and diabetes contribute to DHF's growing incidence.

Purpose of the Study:

  • To analyze the current prevalence and mortality rates of diastolic heart failure (DHF).
  • To highlight the significant public health implications of DHF.
  • To emphasize the need for risk factor reduction and further research into DHF pathophysiology and treatment.

Main Methods:

  • Review of contemporary cohort studies and retrospective analyses.
  • Analysis of data from the Cardiovascular Health Study.
  • Examination of mortality data associated with DHF admissions.

Main Results:

  • Diastolic heart failure (DHF) prevalence is high and increasing.
  • One-year all-cause mortality after DHF admission is substantial (22-29% in retrospective studies).
  • DHF contributes significantly to overall heart failure mortality due to a large patient population.

Conclusions:

  • Diastolic heart failure (DHF) is a growing public health concern with high and rising prevalence.
  • Mortality associated with DHF is comparable to systolic heart failure.
  • Intensified efforts to manage risk factors and conduct prospective trials are crucial for understanding and treating DHF.