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Published on: April 19, 2022

Perioperative haemostatic management of Glanzmann thrombasthenia for abdominal surgery

Susanne Lison1, Michael Spannagl, Bernhard Heindl

  • 1Department of Anesthesiology, Ludwig Maximilians University of Munich, Munich, Germany. susanne.lison@med.uni-muenchen.de

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|April 16, 2009
PubMed

Glanzmann thrombasthenia is a rare congenital platelet disorder characterized by spontaneous mucocutaneous bleeding and severe bleeding complications during major surgery. This report centres on the perioperative haemostatic management of a patient with Glanzmann thrombasthenia undergoing elective major abdominal surgery. The treatment regimen was based mainly on recombinant activated factor VII, fibrinogen, and factor XIII, reducing platelet transfusion to a minimum. No red blood cell transfusions were needed perioperatively. For haemostatic monitoring, routine laboratory tests were sufficient.

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