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Updated: Jun 24, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Endoscopic closure of gastrointestinal leaks
1Department of Gastroenterology, Hepatology, and Nutrition-Unit 1466, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030-4009, USA. gsraju@mdanderson.org
Abstract:
Surgery has been the mainstay of therapy in patients with gastrointestinal perforations. This paradigm started to shift with the development of techniques for endoscopic closure of gastrointestinal perforations. A detailed review of the literature on this subject, along with a commentary on practical aspects in the management of patients with gastrointestinal leaks, is provided here.
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