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Updated: Jun 24, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Tacalcitol ointment for the treatment of nail psoriasis
Gemma Márquez Balbás1, Manuel Sánchez Regaña, Pablo Umbert Millet
1Dermatology Department, University Hospital of Sagrat Cor, Barcelona, Spain. 40871gmb@comb.cat
Abstract:
Tacalcitol is a vitamin D analog with proven efficacy for the topical treatment of psoriasis, but to date it has not been tested in psoriasis of the nail. However, successful treatment has been reported with other vitamin D derivatives such as topical calcipotriol, and topical calcitriol in one study. The present study aimed to assess the efficacy and tolerability of topical tacalcitol in the treatment of nail psoriasis in a sample of 15 patients over a 6-month period. Treatment with tacalcitol ointment may be useful to treat nail psoriasis as it achieves a significant improvement in all nail parameters, both of the matrix and of the bed.
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