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Updated: Jun 24, 2026

Low-intensity Blast Wave Model for Preclinical Assessment of Closed-head Mild Traumatic Brain Injury in Rodents
Published on: November 6, 2020
A finite element study of blast traumatic brain injury - biomed 2009
Jiangyue Zhang1, Narayan Yoganandan, Frank A Pintar
1Medical College of Wisconsin and VA Medical Center,Milwaukee, WI.
Abstract:
An idealized finite element human head model was constructed to study biomechanical responses in the brain due to blast overpressure loading from a blast of 10 kg TNT at 1 meter. Brain strain in the coup and contrecoup regions were 4-7x higher than the central region, and high brain strain (15%) large deformation (4 mm) occurred in the brainstem region, indicating a higher probability of injury in the peripheral brain and brainstem regions due to blast overpressure loading.

