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Updated: Jun 24, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Perioperative management of patients suffering from sleep-related breathing disorders]
F Dette1, M Zoremba, J Heitmann
1Klinik für Anästhesie und Intensivtherapie, Universitätsklinikum Giessen und Marburg GmbH, Standort Marburg, 35033 Marburg. Frank.Dette@web.de
Abstract:
Sleep-related breathing disorders have been associated with increased perioperative morbidity and mortality. The respective patients are at risk during two independent periods. Besides an early period, characterised by the influence of anaesthetics, patients are at risk also during a late period, which is characterised by nocturnal desaturation and disturbances of the cardiovascular system, caused by interference with the sleep architecture, especially of the REM sleep. To assure a safe perioperative management, a close monitoring (O2 saturation and pCO2) and the option for non-invasive ventilation have to be guaranteed.
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