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Related Concept Videos

Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...

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Updated: Jun 23, 2026

Determination of the Absorption, Translocation, and Distribution of Imidacloprid in Wheat
06:11

Determination of the Absorption, Translocation, and Distribution of Imidacloprid in Wheat

Published on: April 28, 2023

Imidacloprid poisoning: a case report.

Ashish Kumar Panigrahi1, D K S Subrahmanyam, Kiran K Mukku

  • 1Department of Medicine, Jipmer, Pondicherry. ashpani@gmail.com

The American Journal of Emergency Medicine
|April 18, 2009
PubMed
Summary
This summary is machine-generated.

Imidacloprid insecticide poisoning can cause respiratory arrest, requiring mechanical ventilation. This case report highlights a patient

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Area of Science:

  • Toxicology
  • Neuroscience

Background:

  • Imidacloprid is a widely used systemic chloronicotinyl insecticide.
  • It acts by blocking acetylcholine receptors, with generally low human toxicity.
  • Limited case reports exist on severe human poisoning outcomes.

Observation:

  • A patient presented with severe poisoning after imidacloprid exposure.
  • The poisoning led to respiratory arrest, necessitating mechanical ventilation.
  • The patient ultimately recovered fully from the toxic effects.

Findings:

  • This report details a rare instance of severe imidacloprid-induced respiratory arrest.
  • The case underscores the potential for significant neurotoxic effects despite general safety perceptions.
  • Successful recovery was achieved with supportive mechanical ventilation.

Implications:

  • Highlights the importance of considering imidacloprid in differential diagnoses for unexplained respiratory failure.
  • Suggests that mechanical ventilation is a viable supportive treatment for severe cases.
  • Emphasizes the need for continued vigilance and research into the neurotoxic potential of insecticides.