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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

Human Th17 cells in infection and autoimmunity

Federica Sallusto1, Antonio Lanzavecchia

  • 1Institute for Research in Biomedicine, Bellinzona, Switzerland. federica.sallusto@irb.unisi.ch

Microbes and Infection
|April 18, 2009
PubMed

IL-17-producing T cells (Th17) have been identified in mice as a distinct lineage of CD4(+) T helper cells. Since their discovery, efforts have been made in characterizing human Th17 cells and the factors involved in their differentiation and in understanding the role these cells play in protective immunity and autoimmune diseases.

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