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[Potassium permanganate poisoning in infancy].

E Hershkovitz¹, Z Weizman

¹Dept. of Pediatrics, Soroka Medical Center, Beer Sheba.

|May 1, 1991

Summary

Accidental potassium permanganate ingestion in infants can cause oral burns and leukocytosis. Prompt management with water lavage and monitoring prevented severe complications in three infant girls.

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Area of Science:

Toxicology
Pediatric Medicine
Emergency Medicine

Background:

Potassium permanganate is a strong oxidizing agent with potential toxicity.
Accidental ingestion in infants is a rare but serious concern.
Similar packaging of household products can lead to medication errors.

Observation:

Three infant girls (2.5, 2.5, and 5 months) presented with potassium permanganate intoxication.
Two cases resulted from mistaking the solution for vitamin A+D preparation due to similar packaging.
Clinical symptoms included restlessness, low-grade fever, and oral mucosa inflammation with black-brown discoloration.

Findings:

Leukocytosis with a left shift was observed in the affected infants.
Severe complications like hepatic/renal damage, airway obstruction, GI ulceration, bleeding, methemoglobinemia, and hemolysis were notably absent.
Management involved hemodynamic and respiratory monitoring, water lavage, and milk ingestion.

Implications:

Early recognition and prompt, conservative management are crucial for favorable outcomes in pediatric potassium permanganate intoxication.
The study highlights the importance of product packaging awareness to prevent accidental ingestions in infants.
Absence of severe complications suggests that timely intervention can mitigate the risks associated with this poisoning.

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