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Dural venous thrombosis following splenectomy in a patient with hereditary spherocytosis

Linda A Perkins1, Shirley F Jones, Ranjana S Bhargava

  • 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of South Carolina, Eight Medical Park, Columbia, SC 29203, USA. Linda.Perkins@uscmed.sc.edu

Southern Medical Journal
|April 18, 2009
PubMed

Hereditary spherocytosis is a common form of hemolytic anemia sometimes requiring splenectomy in recalcitrant cases. The complications of splenectomy include an increased risk of thrombosis, usually presenting with deep vein thrombosis or pulmonary embolism. However, common complaints such as headache should warn clinicians of involvement in less common sites, primarily the dural venous system. The case of dural venous thrombosis in a patient with hereditary spherocytosis and splenectomy is discussed. The potential mechanisms associated with thrombosis formation in this population and its treatment are discussed.

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