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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

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Related Experiment Video

Updated: Jun 23, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Deep sclerectomy and trabeculectomy in uveitic glaucoma.

B Dupas1, C Fardeau, N Cassoux

  • 1Department of Ophthalmology, Pitié Salpétrière Hospital, AP-HP, Paris, France. benedicte.dupas@gmail.com

Eye (London, England)
|April 18, 2009
PubMed
Summary

Deep sclerectomy (DS) and trabeculectomy (TRAB) offer similar intraocular pressure (IOP) control for uveitic glaucoma. While TRAB causes more inflammation, DS requires more postoperative adjustments for effective IOP management.

Related Experiment Videos

Last Updated: Jun 23, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Area of Science:

  • Ophthalmology
  • Glaucoma Management
  • Uveitis Research

Background:

  • Uveitic glaucoma presents a significant challenge in managing intraocular pressure (IOP).
  • Surgical interventions are often necessary when medical management fails.

Purpose of the Study:

  • To compare the efficacy and safety of deep sclerectomy (DS) with trabeculectomy (TRAB) in patients with uveitic glaucoma.
  • To evaluate outcomes such as IOP control, inflammation, and complication rates.

Main Methods:

  • A retrospective chart review of 41 eyes (38 patients) with uncontrolled uveitic glaucoma.
  • Surgical procedures included DS with an implant (20 eyes) and TRAB (21 eyes), both using antiproliferative agents.
  • Key outcome measures included IOP, flare values, complications, and need for re-operation.

Main Results:

  • Both DS and TRAB demonstrated comparable IOP control at 12 months post-surgery (DS: 11.7+/-3.3 mm Hg, TRAB: 12.4+/-4.3 mm Hg).
  • Cumulative success rates at 12 months were similar (DS: 88%, TRAB: 89%).
  • Deep sclerectomy required significantly more postoperative adjustments (85% vs 9.5%) but resulted in less intraocular inflammation 7 days post-surgery compared to trabeculectomy.

Conclusions:

  • Deep sclerectomy and trabeculectomy provide equivalent IOP control for uveitic glaucoma.
  • Trabeculectomy is associated with greater postoperative inflammation, while deep sclerectomy necessitates closer monitoring and more adjustments for successful IOP management.