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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Cerebral venous thrombosis treated with enoxaparin in an IUGR neonate with DIC
1Neonatal Intensive Care Unit, Department of Critical Care Medicine and Surgery, Azienda Ospedaliera Universitaria Careggi, Viale Morgagni 85, 50134, Florence, Italy. giovanna.bertini@unifi.it
Background:
The case of a term IUGR newborn who presented a cerebral vein thrombosis diagnosed by routine ultrasound brain scan, and confirmed by magnetic resonance imaging and magnetic resonance venography, is reported. A thrombosis of cortical cerebral veins and intracerebral haemorrhage in the right frontal paramedian region was observed.
Methods:
Treatment with enoxaparin was started at the initial dose of 0.5 mg/kg subcutaneously every 12 h and then at 1.25 mg/kg per 12 h in order to obtain anti-factor Xa levels between 0.5 and 1.0 U/ml. After hospital discharge, enoxaparin was continued for 2 months with a lower dose (1.8 mg/kg/die).
Conclusion:
Treatment with enoxaparin was effective as demonstrated by a complete "restitutio ad integrum".
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