Related Experiment Video
Updated: Jun 23, 2026

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline
Published on: January 5, 2017
Molecular modelling study of the 3D structure of the bovine viral diarrhea virus (BVDV) helicase
Andrea Brancale1, Chrisanthy Vlachaki, Dimitrios Vlachakis
1Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10 3XF, UK.
Abstract:
Bovine viral diarrhea virus (BVDV) is a member of the Flaviviridae family of viruses and constitutes a very important pathogen for livestock around the world. The viral helicase is an enzyme essential for the proliferation and transmission of the virus. In this work a 3D-model of the BVDV helicase was produced using homology modelling techniques and the known 3D-structure of the hepatitis C helicase of the Flaviviridae family as template, in an attempt to provide the means for structure-based design of novel anti-BVDV agents.
Related Concept Videos
Size and Structure of Viral Genomes
Viral Structure
DNA Helicases
Inhibitors of Virion Maturation and Assembly
Nucleic Acid Structure
DNA Structure
DNA has a double-helix structure. The...
Protein Complex Assembly
Many viruses self-assemble into a fully functional unit using the infected host cell to...

