Related Experiment Video
Updated: Jun 23, 2026

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
Ropivacaine peritonsillar infiltration for analgesia after adenotonsillectomy in children: a randomized,
Marco Gemma1, Lucia Oriella Piccioni, Luigi Gioia
1Anesthesia and Intensive Care Unit for Head and Neck Surgery, Scientific Institute Hospital S. Raffaele, Milan, Italy.
Insights
Peritonsillar infiltration with ropivacaine did not significantly reduce pain after adenotonsillectomy in children. This study found no major postoperative analgesic effect, though minor pain relief may occur at 6 hours.
Area of Science:
- Anesthesiology
- Pediatric Surgery
Background:
- Adenotonsillectomy is a common pediatric surgical procedure.
- Effective postoperative pain management is crucial for recovery in children.
Purpose of the Study:
- To evaluate the efficacy of peritonsillar infiltration with ropivacaine for postoperative pain relief after adenotonsillectomy in children aged 3-7 years.
- To compare pain levels and analgesic requirements between ropivacaine and placebo groups.
Main Methods:
- A randomized, double-blind, placebo-controlled study involving sixty children (3-7 years old) undergoing adenotonsillectomy.
- Intraoperative peritonsillar infiltration with either 0.75% ropivacaine or saline.
- Postoperative pain assessment using the Faces Pain Scale at 6 and 24 hours, and recording of acetaminophen-codeine doses.
Main Results:
- No significant difference in pain scores was observed between the ropivacaine and saline groups at 6 or 24 hours post-surgery.
- The number of acetaminophen-codeine doses required was similar in both groups.
Conclusions:
- Peritonsillar infiltration with 0.75% ropivacaine does not provide a significant postoperative analgesic effect in children undergoing adenotonsillectomy.
- A potential, though minor, analgesic effect may be present at 6 hours post-surgery.
Objectives:
Our randomized, double-blind, placebo-controlled study evaluates the possible benefit of peritonsillar infiltration with 0.75% ropivacaine hydrochloride on the pain level after adenotonsillectomy in 3- to 7-year-old children.
Methods:
We randomly administered intraoperative peritonsillar infiltration with 0.2 mL/kg ropivacaine 0.75% (group R) or 0.2 mL/kg saline 0.9% (group F) to sixty 3- to 7-year-old children (ASA 1 or 2) who were undergoing adenotonsillectomy. Postoperative pain was assessed 6 and 24 hours after surgery by a 6-face Faces Pain Scale that allowed quantification of pain on a 100-mm horizontal line (0 = no pain). The number of rectal doses of acetaminophen-codeine required during the first postoperative day was recorded.
Results:
The pain scores did not differ between the groups, either 6 or 24 hours after surgery (group F, 43 +/- 26, versus group R, 29 +/- 23, and group F, 24 +/- 23, versus group R, 30 +/- 28, respectively). Acetaminophen-codeine doses were similarly required in the two groups.
Conclusions:
Peritonsillar infiltration with 0.75% ropivacaine does not provide any major postoperative analgesic effect in 3- to 7-year-old children after adenotonsillectomy. A possible clinically minor analgesia 6 hours after surgery is suggested.
Related Concept Videos
Tonsillitis II: Management
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Parenteral Anesthetics: Overview
Local Anesthetics: Clinical Application as Spinal Anesthesia
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.