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Related Concept Videos

Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
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Related Experiment Video

Updated: Jun 23, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

Noninvasive pulmonary Aspergillus infections.

Brent P Riscili1, Karen L Wood

  • 1Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, The Ohio State University Medical Center, Davis Heart and Lung Research Institute, Columbus, OH 43210, USA.

Clinics in Chest Medicine
|April 21, 2009
PubMed
Summary

This review covers noninvasive pulmonary Aspergillus infections like ABPA, aspergilloma, and CPA. It details their clinical presentation, diagnosis, pathogenesis, and treatment, focusing on host immune factors.

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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
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Last Updated: Jun 23, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Area of Science:

  • Pulmonology
  • Mycology
  • Infectious Diseases

Background:

  • Aspergillus species cause various pulmonary diseases, influenced by host lung and immune status.
  • Noninvasive forms include Allergic Bronchopulmonary Aspergillosis (ABPA), Aspergilloma, and Chronic Pulmonary Aspergillosis (CPA).

Purpose of the Study:

  • To review the clinical presentation, diagnosis, pathogenesis, and treatment of noninvasive pulmonary Aspergillus infections.
  • To differentiate between ABPA, Aspergilloma, and CPA based on host factors and clinical characteristics.

Main Methods:

  • Literature review of clinical presentations.
  • Review of diagnostic approaches.
  • Analysis of pathogenesis and treatment strategies for noninvasive Aspergillus infections.

Main Results:

  • ABPA results from a hypersensitivity reaction to Aspergillus, often in asthma or cystic fibrosis patients.
  • Aspergillomas are fungal balls in pre-existing lung cavities, commonly post-tuberculosis.
  • CPA, or semi-invasive aspergillosis, typically affects individuals with underlying lung disease or mild immunosuppression.

Conclusions:

  • Understanding host factors is crucial for differentiating and managing noninvasive pulmonary Aspergillus infections.
  • Accurate diagnosis and tailored treatment are essential for improving outcomes in patients with ABPA, Aspergilloma, and CPA.