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Prevention of Further Absorption of Poison

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...

Physical Properties of Amines

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Amines with low molecular weight are usually gaseous at room temperature, while those with high molecular weight are liquid or solids in nature. Usually, low molecular weight amines have a rotten fish-like smell. Diamines typically have a pungent smell. For instance, cadaverine and putrescine, depicted in Figure 1, are two molecules responsible for decaying tissue.

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
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Toxidromes: Clinical Features

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Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...

Antidotes

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Drug toxicity: Idiosyncratic Reactions

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Related Experiment Video

Updated: Jun 23, 2026

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Published on: November 22, 2024

[Intoxications specific to the Aquitaine region].

R Bédry¹, S Gromb

¹UHSI, pôle médico-judiciaire, hôpital Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France. regis.bedry@chu-bordeaux.fr

La Revue De Medecine Interne

|April 21, 2009

Summary

Aquitaine, France, experiences unique intoxications from pine processionary caterpillars, venomous marine life, and endemic mushrooms like Tricholoma auratum, which can cause severe rhabdomyolysis.

Area of Science:

Environmental toxicology
Regional pathology

Context:

Aquitaine region's unique environment and traditional activities contribute to specific intoxications.
Identifies three primary intoxication types prevalent in the area.

Purpose:

To highlight and describe intoxications specific to the Aquitaine region.
To inform about environmental and dietary risks in the area.

Summary:

Pine processionary caterpillar (Thaumetopoea pityocampa) envenomations cause skin and ocular issues.
Venomous marine fauna, including jellyfish and weeverfish, present localized risks along the coast.
Endemic mushroom Tricholoma auratum, previously considered edible, has caused severe rhabdomyolysis, with three fatalities confirmed by animal studies.

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Long-term Lethal Toxicity Test with the Crustacean Artemia franciscana

Long-term Lethal Toxicity Test with the Crustacean Artemia franciscana

Published on: April 14, 2012

Ecotoxicological Method with Marine Bacteria Vibrio anguillarum to Evaluate the Acute Toxicity of Environmental Contaminants

Ecotoxicological Method with Marine Bacteria Vibrio anguillarum to Evaluate the Acute Toxicity of Environmental Contaminants

Published on: May 26, 2017

Related Experiment Videos

Last Updated: Jun 23, 2026

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Published on: November 22, 2024

Long-term Lethal Toxicity Test with the Crustacean Artemia franciscana

Long-term Lethal Toxicity Test with the Crustacean Artemia franciscana

Published on: April 14, 2012

Ecotoxicological Method with Marine Bacteria Vibrio anguillarum to Evaluate the Acute Toxicity of Environmental Contaminants

Ecotoxicological Method with Marine Bacteria Vibrio anguillarum to Evaluate the Acute Toxicity of Environmental Contaminants

Published on: May 26, 2017

Impact:

Raises awareness of regional toxicological hazards in Aquitaine.
Informs public health strategies and clinical management of these specific intoxications.