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Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
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Protein 4.1R links E-cadherin/beta-catenin complex to the cytoskeleton through its direct interaction with

Shaomin Yang1, Xinhua Guo, Gargi Debnath

  • 1Red Cell Physiology Laboratory, New York Blood Center, 310 East 67th St., New York, NY 10065, USA.

Biochimica Et Biophysica Acta
|April 21, 2009
PubMed

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Strong contact points between adjacent cells anchor them to each other, forming tissues. Such anchoring junctions are of two types –  adherens junctions and desmosomes. Adherens junctions are abundant in tissues such as  epithelium and endothelium, forming a continuous zone of adhesion called the adhesion belt. In other tissues, such as  heart muscle, they appear as clusters, linking the cells to produce coordinated heart muscle contraction.
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