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[Hypersensitivity pneumonitis caused by Mucor species in a cork worker]
Ana Villar1, Xavier Muñoz, Maria Jesus Cruz
1Servei de Pneumologia, Hospital Vall d'Hebron, Departamento de Medicina, Universitat Autònoma de Barcelona, Barcelona, España.
Abstract:
Suberosis is a type of hypersensitivity pneumonitis caused by exposure to cork proteins and molds such as Aspergillus fumigatus and Penicillium frequentans. We present the case of a man with suberosis caused by Mucor species, a mold that has been rarely reported to cause hypersensitivity pneumonitis. Furthermore, the patient had symptoms and lung function tests indicating bronchial obstruction-an atypical presentation of hypersensitivity pneumonitis. No imaging abnormalities were observed. A diagnosis was made on the basis of bronchoalveolar lavage and transbronchial biopsy findings. Mucor species was identified as the causative agent using a specific bronchial challenge test.
Insights
This study details a rare case of suberosis, a lung disease caused by mold exposure. The patient presented with bronchial obstruction due to Mucor species, an unusual cause of hypersensitivity pneumonitis.
Area of Science:
- Pulmonary Medicine
- Immunology
- Mycology
Background:
- Suberosis is a form of hypersensitivity pneumonitis typically linked to cork and common mold exposure.
- Hypersensitivity pneumonitis (HP) can manifest in various ways, often affecting lung parenchyma.
Observation:
- A patient presented with symptoms and lung function tests indicative of bronchial obstruction.
- The patient's presentation was atypical for hypersensitivity pneumonitis, with no observable abnormalities on imaging.
- Diagnosis was confirmed through bronchoalveolar lavage and transbronchial biopsy.
Findings:
- Mucor species was identified as the causative agent of suberosis in this patient.
- This represents a rare instance of Mucor species inducing hypersensitivity pneumonitis.
- A bronchial challenge test specifically identified Mucor species as the trigger.
Implications:
- Highlights Mucor species as a potential, albeit rare, cause of hypersensitivity pneumonitis.
- Emphasizes the importance of considering atypical presentations, such as bronchial obstruction, in diagnosing HP.
- Suggests the utility of bronchial challenge tests in identifying specific mold triggers for HP.
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