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A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
Published on: May 25, 2017
A simple 3-step algorithm for improved laboratory detection of Clostridium difficile toxin without the need for
Susan E Sharp1, W Michael Ivie, Misti R Buckles
1Kaiser Permanente NW, Department of Pathology, Portland, OR 97230, USA. susan.e.sharp@kp.org
Diagnostic Microbiology and Infectious Disease
|April 21, 2009
Abstract:
This report describes a 3-step algorithm for the detection of Clostridium difficile using an enzyme immunoassay for glutamate dehydrogenase (GDH) antigen, a lateral flow assay for C. difficile toxin, and anaerobic broth culture. This method was found to detect more toxin-containing stool samples than the use of a combination GDH antigen plus toxin A/B testing alone.
