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Related Concept Videos

Asymmetric Lipid Bilayer01:35

Asymmetric Lipid Bilayer

Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
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Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich with the analogy of...
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Flippase
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Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes
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Published on: December 15, 2015

Spraying asymmetry into functional membranes layer-by-layer.

Kevin C Krogman1, Joseph L Lowery, Nicole S Zacharia

  • 1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Nature Materials
|April 21, 2009
PubMed
Summary
This summary is machine-generated.

Engineers developed an economical spray-assisted technique to create advanced textile membranes with tunable nanoscale properties. This method enables diverse applications, from gas purification to tissue engineering scaffolds.

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Nanotechnology

Background:

  • Mimicking natural materials with synthetics is challenging due to processing costs and complexity.
  • Current methods often limit innovation in creating multifunctional materials.
  • Textile membranes offer a versatile platform for material engineering.

Purpose of the Study:

  • To present a cost-effective technique for creating multifunctional textile membranes.
  • To enable precise engineering of material properties at the nanoscale.
  • To demonstrate the versatility of the technique for various applications.

Main Methods:

  • Utilizing spray-assisted layer-by-layer deposition on electrospun materials.
  • Controlling the flow rate of charged species to vary coating morphology and function.
  • Developing conformal functionalization and networked sublayers on individual fibers.

Main Results:

  • Achieved multiple coatings with different morphologies and functions on a single textile membrane.
  • Demonstrated ultrahigh-surface-area catalysis through conformal fiber functionalization.
  • Created networked sublayers with complementary properties by bridging fibers.

Conclusions:

  • The developed technique is powerful, economical, and scalable for commercial viability.
  • This method allows for significant engineering of material properties from the nanoscopic level.
  • Potential applications include advanced gas purification, self-cleaning fabrics, water purification, and tissue engineering scaffolds.