Related Experiment Video
Updated: Jun 23, 2026

11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
[Psoriasis in childhood and adolescence]
Ricardo Romiti1, Luciana Maragno, Marcelo Arnone
1Department of Dermatology, Hospital das Clínicas, Universidade de São Paulo, São Paulo, SP, Brazil. rromiti@hotmail.com
Anais Brasileiros De Dermatologia
|April 21, 2009
Summary
Psoriasis, a chronic inflammatory condition, often begins in childhood, impacting quality of life. Early onset correlates with a worse prognosis, necessitating tailored pediatric treatment approaches.
Area of Science:
- Dermatology
- Pediatrics
- Immunology
Background:
- Psoriasis is a chronic, inflammatory disorder with potential early onset.
- Childhood psoriasis can lead to disfigurement, psychological distress, and reduced quality of life.
- Systemic therapies and phototherapy have limitations in pediatric patients due to safety concerns.
Purpose of the Study:
- To review the clinical aspects of psoriasis in children and adolescents.
- To discuss differential diagnoses for pediatric psoriasis.
- To outline therapeutic options and prognosis for childhood psoriasis.
Main Methods:
- Literature review focusing on pediatric psoriasis.
- Analysis of clinical presentation, diagnosis, and treatment strategies.
- Evaluation of prognostic factors in early-onset psoriasis.
Main Results:
- Early-onset psoriasis (before 16) is associated with a poorer prognosis.
- Pediatric psoriasis presents unique challenges for diagnosis and management.
- Limited systemic and phototherapy options exist for children.
Conclusions:
- Psoriasis in children requires specialized clinical assessment.
- Careful consideration of differential diagnoses is crucial.
- Therapeutic strategies must balance efficacy with safety in pediatric populations.
Related Concept Videos
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Psychological and Sociocultural Causes of Schizophrenia
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Chickenpox
Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
Multiple Sclerosis l: Introduction
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Oppositional Defiant Disorder
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...