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Updated: Jun 23, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

[Medium and large vessel vasculitis].

Hebert Roberto Clivati Brandt¹, Marcelo Arnone, Neusa Yuriko Sakai Valente

¹Departamento de Dermatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.

Anais Brasileiros De Dermatologia

|April 21, 2009

Summary

This summary is machine-generated.

Vasculitis involves blood vessel inflammation, leading to narrowing or blockage. This review covers medium and large vessel vasculitis, diagnosis, and treatment for suspected cutaneous cases.

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Area of Science:

Rheumatology and Immunology
Pathology

Context:

Vasculitis encompasses diverse syndromes causing blood vessel inflammation and necrosis.
Classification is based on the size of affected vessels: large, medium, and small.
This review focuses on medium and large vessel vasculitis.

Purpose:

To review medium and large vessel vasculitis.
To discuss current treatment options.
To present a diagnostic and treatment approach for cutaneous vasculitis.

Summary:

Vasculitis is defined by inflammation and necrosis of blood vessel walls, causing lumen narrowing or occlusion.
Syndromes are classified by vessel size: large (e.g., Takayasu arteritis), medium/small muscular arteries (e.g., polyarteritis nodosa), and small vessels (e.g., Henoch-Schonlein purpura).
The article details medium and large vessel vasculitis, current therapies, and diagnostic/treatment strategies for suspected cutaneous involvement.

Impact:

Provides a comprehensive overview of medium and large vessel vasculitis.
Offers guidance on diagnosis and treatment for clinicians.
Aids in understanding the classification and management of vasculitic syndromes.