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In vitro binding of Helicobacter pylori to human gastric mucin
L S Tzouvelekis1, A F Mentis, A M Makris
1Department of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
Infection and Immunity
|November 1, 1991
Abstract:
The in vitro binding of four Helicobacter pylori strains to human gastric mucin was studied with an enzyme-linked immunosorbent assay. All four strains were found to bind to purified mucin. Neuraminidase treatment and nonspecific oxidation of mucin decreased bacterial adherence to the macromolecule. Mucin preparations were also found to inhibit attachment of H. pylori to HEp-2 monolayers.