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Updated: Jun 23, 2026

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Inflammatory responses after percutaneous coronary intervention in patients with acute myocardial infarction or
S Solheim1, H K Grøgaard, P Hoffmann
1Department of Cardiology, Ullevål University Hospital, Oslo, Norway. s-solh@online.no
Objective:
To investigate the profile of circulating inflammatory markers after percutaneous coronary intervention (PCI) in patients with AMI or stable angina pectoris (AP).
Material And Methods:
Twenty patients with AMI and 10 with stable AP were treated with PCI of a central coronary artery. Blood samples were drawn immediately before PCI, in the AP group and after 3 and 12 h, days 1, 3, 5, 7 and 14 in both groups.
Results:
Interleukin 6 increased in both groups to time-point 12 h and day 1 (peak), being significantly higher in the AMI group compared to the AP group at 3 and 12 h, and also at days 1 and 3. A similar profile was demonstrated for CRP with significantly higher levels in the AMI group at days 1, 3 and 5 compared to the AP group. A slightly different pattern was shown for Interleukin 10 (IL-10) with significantly higher levels in the AMI group at 3 and 12 h, days 1 and 14 compared to the AP group.
Conclusion:
AMI patients treated with PCI experienced a marked short-term increase in pro-inflammatory mediators as well as IL-10 compared to patients with stable angina pectoris treated with PCI.
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