[Gastric metastasis from renal cell carcinoma 20 months after radical nephrectomy: a case report]

Metastatic lesions from renal cell carcinoma (RCC) commonly occur in the lung and bone, gastric metastasis has rarely been reported in the literature. We present herein a case of a man with gastric metastasis from RCC. A 49-year-old male was admitted to our hospital complaining of dyspnea on exercise. He had undergone right radical nephrectomy due to RCC two years ago (T3a NO MI), followed by postoperative immunotherapy with interferon-alpha and interleukin 2. Gastrointestinal endoscopy revealed a solitary polypoid lesion about 20 mm in diameter in the greater curvature of the middle gastric body. Endoscopic needle biopsy revealed poorly differentiated adenocarcinoma. Partial gastrectomy was performed and histologic examination of the resected specimen confirmed diagnosis of clear cell renal carcinoma. Metastasis of any cancer to the stomach is quite uncommon. In particular, gastric metastasis from RCC is extremely rare. To our knowledge, this is the 15th case of gastric metastasis from RCC reported in Japan.