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4D Printed Bifurcated Stents with Kirigami-Inspired Structures
Published on: July 25, 2019
Perspective on bifurcation PCI
Shao-Liang Chen1, Yves Louvard, Gao Runlin
1Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. chmengx@126.com
Insights
Coronary bifurcation lesions pose challenges, lacking a guiding classification. This review explores various stenting strategies and dedicated stents for improved outcomes.
Area of Science:
- Interventional Cardiology
- Cardiovascular Surgery
Background:
- Coronary bifurcation lesions present complex challenges in interventional cardiology, often leading to suboptimal outcomes.
- Current classifications inadequately guide treatment selection and outcome prediction for these lesions.
- Significant differences exist between left main (LM) bifurcation and non-LM bifurcation lesions.
Purpose of the Study:
- To provide a historical overview of coronary bifurcation lesion interventions.
- To analyze the strengths and weaknesses of various stenting strategies.
- To review the development and clinical evaluation of dedicated bifurcated stents.
Main Methods:
- Literature review of historical interventions for coronary bifurcation lesions.
- Analysis of proposed and trialed stenting techniques (e.g., V, T, Y, one-stent, two-stent, crush, mini-crush, DK, SKS).
- Evaluation of dedicated bifurcated stents developed to simplify procedures.
Main Results:
- Numerous stenting strategies have been developed, but many are time- and labor-intensive.
- Dedicated bifurcated stents have been engineered and trialed to address procedural complexity.
- A comprehensive understanding of strategy effectiveness and stent performance remains crucial.
Conclusions:
- Effective management of coronary bifurcation lesions requires careful consideration of available strategies and devices.
- The evolution towards dedicated stents aims to improve procedural efficiency and patient outcomes.
- Further research and standardized classifications are needed for optimal treatment selection and prediction.
Abstract:
Coronary bifurcation lesion is a complex lesion with suboptimal angiographic and clinical results. There has been no satisfactory classification of the lesion that can guide selection of strategies and predict short- and long-term outcomes. The difference between left main (LM) bifurcation lesions and non-LM bifurcation is striking. So many stenting strategies have been proposed and tried in trials. They include the V, T, Y, one-stent, two-stent, crush, mini-crush, DK, and SKS techniques. However, because these techniques are time and labor intensive, dedicated bifurcated stents have been invented and trialed in humans. This review presents a historical perspective of interventions in bifurcated lesions, with the strengths and weaknesses of the major strategies and of the new dedicated stents.
