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Updated: Jun 23, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
Published on: January 23, 2026
Postpneumonectomy-like syndrome in an infant with right lung agenesis and left main bronchus hypoplasia
Simone Furia1, Paolo Biban, Monica Benedetti
1Division of Thoracic Surgery, Major City Hospital, Verona, Italy.
Insights
A child with a missing right lung experienced respiratory failure due to mediastinal shift. An expandable prosthesis inserted into the empty chest cavity successfully treated the condition.
Area of Science:
- Pediatric Pulmonology
- Thoracic Surgery
- Medical Device Innovation
Background:
- Congenital agenesis of the right lung presents unique challenges in pediatric respiratory care.
- Postpneumonectomy-like syndrome can arise from significant volume loss in the thoracic cavity.
- Acute respiratory failure in infants requires prompt and innovative management strategies.
Observation:
- A 1-year-old infant with congenital right lung agenesis developed acute respiratory failure.
- Severe mediastinal shift and left main bronchus stenosis were observed.
- The condition mimicked complications typically seen after lung removal surgery.
Findings:
- The insertion of an expandable prosthesis into the right hemithorax was performed.
- This intervention effectively addressed the mediastinal shift and bronchial stenosis.
- The patient's clinical condition significantly improved post-procedure.
Implications:
- Expandable prostheses offer a novel therapeutic option for managing postpneumonectomy-like syndromes in pediatric patients with congenital lung absence.
- This approach may prevent or reverse bronchial compromise caused by thoracic volume discrepancies.
- Further research into the long-term efficacy and safety of such devices is warranted.
Abstract:
We report a 1-year-old child born with agenesis of the right lung who sustained an episode of acute respiratory failure related to a postpneumonectomy-like syndrome, with severe mediastinal shift and subsequent stretching and stenosis of the left main bronchus. The insertion of an expandable prosthesis in the right empty pleural space markedly improved the patient's clinical condition.
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