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MicroRNA-based Regulation of Picornavirus Tropism
Published on: February 6, 2017
All for one and one for all: herpesviral microRNAs close in on their prey
1Max von Pettenkofer-Institut, Pettenkoferstrasse 9a, München D-80336, Germany.
Cell Host & Microbe
|April 22, 2009
Abstract:
Herpesviruses subvert immune cell activation by inhibiting NK cell receptor (NKG2D)-activating ligands such as MICB. A human cytomegalovirus microRNA was recently shown to repress MICB expression. Nachmani et al. (2009) extend this finding to two other human herpesviruses, providing evidence for a conserved functional role of viral microRNAs despite no sequence conservation among them.
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