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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
Plasticity00:58

Plasticity

Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
Auditory Pathway01:15

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...

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Related Experiment Video

Updated: Jun 23, 2026

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
09:06

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Published on: January 9, 2019

Cortical development, plasticity and re-organization in children with cochlear implants.

Anu Sharma1, Amy A Nash, Michael Dorman

  • 1Brain and Behavior Laboratory, Department of Speech, Language and Hearing Sciences, University of Colorado at Boulder, 2501 Kittredge Loop Road, 409 UCB, Boulder, CO 80309-0409, USA. anu.sharma@colorado.edu

Journal of Communication Disorders
|April 22, 2009
PubMed
Summary

The sensitive period for auditory development is crucial for cochlear implant success in children. Understanding this period and using biomarkers like the P1 response aids in central auditory system development and reorganization.

Related Experiment Videos

Last Updated: Jun 23, 2026

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
09:06

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Published on: January 9, 2019

Area of Science:

  • Developmental neurobiology
  • Auditory neuroscience
  • Neuroplasticity

Background:

  • The development of central auditory pathways relies on timely sensory input during critical sensitive periods.
  • Auditory deprivation can lead to de-coupling and re-organization of cortical areas, potentially impacting the end of these sensitive periods.

Observation:

  • This article examines age cut-offs for the sensitive period in children receiving cochlear implants.
  • It reviews mechanisms of cortical re-organization, including de-coupling and cross-modal plasticity, following prolonged auditory deprivation.

Findings:

  • The P1 cortical auditory evoked potential serves as a biomarker for central auditory system development.
  • Case studies illustrate the utility of the P1 response in tracking auditory development and re-organization in congenitally deaf children with cochlear implants.

Implications:

  • Identifying sensitive period cut-offs can optimize cochlear implant timing for better outcomes.
  • The P1 response offers a valuable tool for monitoring neuroplasticity and guiding auditory rehabilitation strategies.
  • Understanding cortical re-organization is key to addressing the long-term effects of auditory deprivation.