Childhood Burkitt lymphoma: abdominal and pelvic imaging findings

David M Biko1, Sudha A Anupindi, Andrea Hernandez

  • 1Department of Radiology, Pennsylvania Hospital, 800 Spruce Street, Philadelphia, PA 19107, USA. david.biko@uphs.upenn.edu

Insights

Pediatric Burkitt lymphoma presents with diverse abdominopelvic imaging findings. Recognizing these patterns is crucial for timely diagnosis and treatment of this aggressive childhood cancer.

Area of Science:

  • Pediatric oncology
  • Abdominal imaging
  • Lymphoma research

Background:

  • Burkitt lymphoma (BL) is an aggressive non-Hodgkin lymphoma with a predilection for children.
  • It can manifest as localized or disseminated disease, affecting various organs.
  • Abdominal and pelvic involvement is common in pediatric BL.

Purpose of the Study:

  • To review the clinical presentation of Burkitt lymphoma in children.
  • To detail the abdominopelvic imaging findings associated with pediatric Burkitt lymphoma.
  • To enhance the recognition of imaging features for improved diagnosis.

Main Methods:

  • Retrospective review of pediatric cases with confirmed Burkitt lymphoma.
  • Analysis of clinical data including presenting symptoms and laboratory results.
  • Comprehensive evaluation of abdominopelvic imaging studies (CT, MRI, Ultrasound).

Main Results:

  • Common sites of involvement include the gastrointestinal tract (ileocecal region, small bowel) and solid organs (liver, spleen, kidneys).
  • Imaging findings can range from focal masses to diffuse infiltration, often with characteristic enhancement patterns.
  • Associated findings may include ascites, lymphadenopathy, and omental caking.

Conclusions:

  • Abdominopelvic imaging reveals numerous findings in pediatric Burkitt lymphoma involving the GI tract and solid organs.
  • Early recognition of both common and uncommon imaging features is vital for prompt diagnosis.
  • Timely diagnosis through imaging is critical for initiating effective and life-saving therapy in pediatric patients.
Abstract

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