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State of the Art Cranial Ultrasound Imaging in Neonates
10:02

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

Neonatal ruptured intracranial aneurysms: case report and literature review

Y Van Raay1, S Darteyre, F Di Rocco

  • 1Department of Paediatric Neurosurgery, Hôpital Necker Enfants-Malades, 149 rue de Sèvres, Paris 75015, France.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|April 22, 2009
PubMed

Insights

Neonatal intracranial aneurysms are rare, with this study detailing the first posterior inferior cerebellar artery (PICA) aneurysm case. Early diagnosis and treatment of these rare PICA aneurysms are crucial for better outcomes in infants.

Area of Science:

  • Neuroscience
  • Pediatric Neurology
  • Vascular Surgery

Background:

  • Intracranial aneurysms are exceedingly rare in neonates, with only 16 prior reported cases.
  • This report details the first documented case of a neonatal posterior inferior cerebellar artery (PICA) aneurysm.

Observation:

  • A 7-day-old infant presented with non-specific symptoms including irritability, anorexia, fever, and rapid head growth.
  • Imaging revealed intraventricular hemorrhage, hydrocephalus, and a pontine cistern hematoma, with a suspected PICA aneurysm confirmed by angiography.

Findings:

  • The infant underwent successful surgical clipping and aneurysm excision.
  • Histopathology showed a calcified arterial wall with thrombosis and absence of the internal elastic lamina, suggesting a congenital origin.

Implications:

  • Neonatal intracranial aneurysms often present with nonspecific symptoms, necessitating prompt diagnostic evaluation.
  • Posterior circulation and large aneurysms are more common in neonates; early intervention improves outcomes, and surgery is generally well-tolerated.
  • Recommended diagnostic pathway includes cranial ultrasound, MR angiography, and CT angiography if needed.
Abstract

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