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A cDNA microarray analysis identifies 52 genes associated with cis-diamminedichloroplatinum susceptibility in head

Takenori Ogawa1, Toru Furukawa, Kiyoto Shiga

  • 1Department of Molecular Pathology, Tohoku University School of Medicine, Sendai Miyagi 980-8575, Japan. ogawa@orl.med.tohoku.ac.jp

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|April 22, 2009
PubMed

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...