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Acute acalculous cholecystitis.

J C Coelho1, A C Campos, M Moreira

  • 1Department of Surgery, Federal University of Paraná, Curitiba, Brazil.

International Surgery
|July 1, 1991
PubMed
Summary
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Acute acalculous cholecystitis, often presenting with abdominal pain and fever, affects diverse patient groups. Surgical intervention via cholecystectomy is standard, though complications like gangrene and perforation occur.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Acute acalculous cholecystitis (AAC) is gallbladder inflammation without stones.
  • AAC can occur postoperatively, in patients with comorbidities, or with mechanical obstruction.

Purpose of the Study:

  • To describe the clinical presentation, management, and outcomes of AAC patients.
  • To identify common signs, symptoms, and complications associated with AAC.

Main Methods:

  • Retrospective review of 32 patients diagnosed with AAC.
  • Analysis of patient demographics, clinical features, surgical procedures, and postoperative outcomes.
  • Microbiological analysis of bile specimens.

Main Results:

  • Common symptoms included right upper quadrant pain, nausea, vomiting, fever, and jaundice.

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  • 28.1% of gallbladders showed gangrene; 12.5% had pericholecystic perforation.
  • E. coli was the most frequent bacterial isolate from bile; mortality was 15.6%.

    • Conclusions:

    • AAC presents with varied symptoms and can lead to severe complications.
    • Prompt cholecystectomy is crucial for managing AAC, despite significant postoperative morbidity.