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Gene expression profiling by microarray analysis reveals an important role for caspase-1 in dengue virus-induced

A M A Nasirudeen1, Ding Xiang Liu

  • 1Institute of Molecular and Cell Biology, Proteos, Singapore, Singapore.

Journal of Medical Virology
|April 22, 2009
PubMed

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The Extrinsic Apoptotic Pathway

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The Intrinsic Apoptotic Pathway

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Interactions Between Signaling Pathways

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...