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Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
Published on: July 4, 2011
Nanomolar Hg(II) detection using Nile blue chemodosimeter in biological media
Min Hee Lee1, Soon W Lee, Sang Hoon Kim
1Department of Chemistry, Korea University, Seoul 136-701, Korea.
Organic Letters
|April 23, 2009
Abstract:
A Nile blue-based chemodosimeter (1) was newly synthesized, and its application for detection of the Hg(2+) ion in 100% aqueous solution was demonstrated. Upon its addition into aqueous Hg(2+) ion solution, it exhibited a considerable blue-shift in its absorption and emission spectra, driven by a desulfurization reaction. Detection at an emission of 652 nm was extremely sensitive (less than 1.0 ppb), even in biological media such as blood plasma and albumin.
