Aortic root surgery in septuagenarians: impact of different surgical techniques

Nawid Khaladj1, Rainer Leyh, Malakh Shrestha

  • 1Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany. Khaladj.Nawid@mh-hannover.de

Abstract

Insights

Valve sparing aortic root reimplantation is a safe and effective procedure for septuagenarians, demonstrating lower early and late mortality compared to other aortic root replacement techniques. This approach improves patient outcomes and quality of life.

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Surgery

Background:

  • Septuagenarians undergoing aortic root replacement (ARR) face significant early and late morbidity and mortality risks.
  • Evaluating the safety and impact of different ARR surgical techniques in this elderly population is crucial.

Purpose of the Study:

  • To compare the early and late outcomes of three distinct aortic root replacement techniques in patients aged 70 and above.
  • To assess the impact of mechanical composite grafts, biological composite grafts, and valve sparing aortic root reimplantation on patient survival and complications.

Main Methods:

  • A cohort of 95 patients (mean age 73.8 years) were divided into three groups: mechanical composite graft (MECH), customized biological composite graft (BIO), and valve sparing aortic root reimplantation (REIMPL).
  • Aortic arch replacement was performed in 42.1% of patients.
  • Follow-up was completed in 95.2% of in-hospital survivors.

Main Results:

  • Hospital mortality was significantly lower in the REIMPL group (0%) compared to MECH (15.7%) and BIO (19.7%) groups (p=0.004).
  • Prolonged mechanical ventilation was more frequent in the BIO group (36.4%) than REIMPL (4.5%) and MECH (7%) groups (p=0.013).
  • Late mortality was significantly lower in the REIMPL group (4.5%) compared to MECH (34.8%) and BIO (16.7%) groups (p=0.012) over a mean follow-up of 41 months.

Conclusions:

  • Valve sparing aortic root reimplantation (David I) is a safe and effective surgical option for septuagenarians requiring aortic root replacement.
  • This technique is associated with significantly reduced early and late morbidity and mortality compared to composite graft replacements.
  • The procedure leads to significant improvements in postoperative New York Heart Association class and performance status.

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