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Histone octamer helical tubes suggest that an internucleosomal four-helix bundle stabilizes the chromatin fiber

Timothy D Frouws1, Hugh-G Patterton, Bryan T Sewell

  • 1Department of Biotechnology, University of the Western Cape, Cape Town, South Africa.

Biophysical Journal
|April 23, 2009
PubMed

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Chromatin Packaging02:21

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Each human somatic cell contains 6 billion base-pairs of DNA. Each base-pair is 0.34 nm long, which means that each diploid cell contains a staggering 2 meters of DNA. How is such a long DNA strand packed inside a nucleus measuring only 10 - 20 microns in diameter? 
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