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Related Concept Videos

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...

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Related Experiment Video

Updated: Jun 23, 2026

Simple and Computer-assisted Olfactory Testing for Mice
06:40

Simple and Computer-assisted Olfactory Testing for Mice

Published on: June 15, 2015

A computer-assisted odorized hole-board for testing olfactory perception in mice.

Nathalie Mandairon1, Sébastien Sultan, Nolwen Rey

  • 1Laboratoire deNeurosciences Sensorielles, Comportement, Cognition, Université de Lyon, 50 Avenue Tony Garnier, Lyon F-69007, France. nathalie.mandairon@olfac.univ-lyon1.fr

Journal of Neuroscience Methods
|April 23, 2009
PubMed
Summary

We developed a computerized system for automatic recording of mouse olfactory behavior. This versatile setup efficiently measures various olfactory functions, offering broad applications in research.

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Related Experiment Videos

Last Updated: Jun 23, 2026

Simple and Computer-assisted Olfactory Testing for Mice
06:40

Simple and Computer-assisted Olfactory Testing for Mice

Published on: June 15, 2015

Constructing an Olfactometer for Rodent Olfactory Behavior Studies
08:36

Constructing an Olfactometer for Rodent Olfactory Behavior Studies

Published on: April 11, 2025

Olfactory Behavioral Testing in the Adult Mouse
09:00

Olfactory Behavioral Testing in the Adult Mouse

Published on: January 28, 2009

Area of Science:

  • Neuroscience
  • Behavioral Science
  • Sensory Biology

Background:

  • Olfactory function is crucial for mammalian behavior and survival.
  • Assessing olfactory capabilities in mice typically requires multiple specialized setups.
  • There is a need for integrated, automated systems for comprehensive olfactory testing.

Purpose of the Study:

  • To describe a novel, computerized behavioral setup for systematic and automatic recording of olfactory behaviors in mice.
  • To showcase the system's capability to measure diverse aspects of olfactory function.
  • To demonstrate the setup's utility and broad applicability in olfactory research.

Main Methods:

  • Design and construction of a computerized monitoring system integrated with a hole-board apparatus.
  • Implementation of software for automated data acquisition and analysis.
  • Utilizing various behavioral paradigms including threshold evaluation, generalization, habituation/dishabituation, associative learning, memory, and preference tests.

Main Results:

  • The system successfully recorded performances across a wide range of olfactory behavioral tests.
  • Data demonstrated the system's ability to measure olfactory threshold, learning, memory, and preferences.
  • The setup proved efficient and reliable for automated olfactory assessment in mice.

Conclusions:

  • A single, automated experimental setup provides a powerful and versatile tool for studying mouse olfactory behavior.
  • The described system offers significant advantages in efficiency, scope, and ease of use for olfactory research.
  • This technology has broad applications for advancing our understanding of olfactory systems and related disorders.