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Lyprinol-is it a useful anti-inflammatory agent?
1School of Life Sciences, Queensland University of Technology, GPO Box2434, Brisbane, QLD 4001, Australia.
Evidence-Based Complementary and Alternative Medicine : Ecam
|April 23, 2009
Summary
New Zealand green lipped mussel (Lyprinol) shows anti-inflammatory effects in animal models and may benefit dogs with arthritis. Human trial limitations make Lyprinol
Area of Science:
- Pharmacology
- Marine Biology
- Immunology
Background:
- Lyprinol, a New Zealand green lipped mussel extract, is widely available.
- Extravagant anti-inflammatory claims for Lyprinol have drawn scrutiny from regulatory bodies.
Purpose of the Study:
- To review the anti-inflammatory claims of Lyprinol.
- To evaluate the efficacy and safety of Lyprinol in various inflammatory conditions.
Main Methods:
- Review of existing scientific literature on Lyprinol.
- Analysis of animal models of inflammation.
- Assessment of clinical trial designs for human studies.
Main Results:
- Lyprinol exhibits anti-inflammatory mechanisms and effects in animal models.
- Potential benefits observed in canine arthritis.
- Clinical trials in humans for osteoarthritis and rheumatoid arthritis have design limitations, suggesting small benefits.
- A small benefit was noted for atopic allergy.
- No adverse effects were reported for Lyprinol.
Conclusions:
- Lyprinol possesses anti-inflammatory properties.
- While Lyprinol may offer some benefits, particularly in dogs with arthritis, its efficacy in human inflammatory conditions is not definitively established due to trial limitations.
- Lyprinol appears to be safe, with no reported adverse effects.
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