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Related Experiment Video

Updated: Jun 23, 2026

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

Published on: July 4, 2017

Juvenile Paget's disease.

C K Indumathi¹, Chitra Dinakar, Rakesh Roshan

¹Department of Pediatrics, St Johns Medical College Hospital, Bangalore, India. satgir@sify.com

Indian Pediatrics

|April 23, 2009

Summary

Juvenile Paget's disease (JPD) is a rare genetic disorder causing rapid bone turnover in children. This case highlights a 15-year-old patient with JPD, emphasizing the need for early diagnosis to prevent disease progression.

Area of Science:

Genetics
Pediatrics
Endocrinology

Background:

Juvenile Paget's disease (JPD) is a rare, inherited skeletal disorder.
It is characterized by significantly accelerated bone remodeling, presenting in early childhood.
Early diagnosis is crucial for managing JPD and preventing long-term complications.

Observation:

A case report of a 15-year-old child with typical features of JPD is presented.
The patient remained undiagnosed until adolescence, despite exhibiting characteristic symptoms.
This case underscores the diagnostic challenges associated with rare pediatric bone diseases.

Findings:

The case demonstrates a delayed diagnosis of JPD in a pediatric patient.
Typical clinical and potentially radiological features of JPD were observed.

Related Experiment Videos

Last Updated: Jun 23, 2026

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

Published on: July 4, 2017

The rarity of JPD in Indian medical literature is noted.

Implications:

This case emphasizes the importance of considering rare genetic disorders like JPD in the differential diagnosis of unexplained skeletal abnormalities in children.
Timely diagnosis of JPD is essential to initiate appropriate management and mitigate disease progression.
Reporting this case contributes to the limited literature on JPD, particularly within the Indian subcontinent, raising awareness among clinicians.