Related Experiment Video
Updated: Jun 23, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Acute kidney injury: intravenous fluid to prevent contrast-induced AKI
Steven D Weisbord1, Paul M Palevsky
1Veterans Affairs Pittsburgh Healthcare System, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15240, USA. weisbordsd@upmc.edu
Abstract:
Trials that compared sodium bicarbonate and sodium chloride for the prevention of contrast-induced acute kidney injury have yielded highly conflicting results. The authors of a recent meta-analysis endeavored to provide a definitive assessment of the relative efficacy of these two intravenous fluids.
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