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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

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Related Experiment Video

Updated: Jun 23, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

In vivo video rate optical coherence tomography.

A Rollins, S Yazdanfar, M Kulkarni

    Optics Express
    |April 23, 2009
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a high-speed optical coherence tomography system for real-time imaging. The advanced system enables rapid in vivo visualization of tissues for disease diagnosis and developmental biology research.

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    Doppler Optical Coherence Tomography of Retinal Circulation

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    Last Updated: Jun 23, 2026

    In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
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    Published on: July 24, 2020

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    Doppler Optical Coherence Tomography of Retinal Circulation
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    Doppler Optical Coherence Tomography of Retinal Circulation

    Published on: September 18, 2012

    Area of Science:

    • Biomedical optics
    • Medical imaging technology
    • Ophthalmic imaging

    Background:

    • Optical coherence tomography (OCT) is a valuable non-invasive imaging technique.
    • Achieving video-rate imaging in OCT has been a significant challenge for real-time applications.
    • Advancements in light sources and hardware are crucial for high-speed OCT.

    Purpose of the Study:

    • To develop and present a novel optical coherence tomography (OCT) system capable of imaging at video rates.
    • To detail the theoretical underpinnings and design of a high-speed scanning delay line for OCT.
    • To demonstrate the system's capability for real-time in vivo imaging in relevant biological models.

    Main Methods:

    • Implementation of a high-power broadband light source for enhanced signal.
    • Development of real-time image acquisition hardware.
    • Integration of a high-speed scanning delay line utilizing Fourier-transform pulse shaping technology in the reference arm.
    • Theoretical analysis of low-coherence interferometry with a dispersive delay line.

    Main Results:

    • Demonstration of an optical coherence tomography (OCT) system operating at video rates.
    • Successful real-time in vivo imaging of human skin and eye tissues.
    • Application of the system to image Xenopus laevis, a model organism in developmental biology.

    Conclusions:

    • The developed OCT system achieves unprecedented imaging speeds, enabling real-time visualization.
    • The system shows significant potential for early human disease diagnosis in dermatology and ophthalmology.
    • This technology offers a powerful new tool for in vivo studies in developmental biology.