Related Experiment Video
Updated: Jun 23, 2026
07:34
Layer Microdissection of Tricuspid Valve Leaflets for Biaxial Mechanical Characterization and Microstructural Quantification
Published on: February 10, 2022
Microscopic study of right fibrous annulus.
M Dudziak1, M Skwarek, J Hreczecha
1Noninvasive Cardiovascular Diagnostic Unit, II Chair of Cardiology, Medical University of Gdańsk, Poland.
Folia Morphologica
|April 23, 2009
Summary
The fibrous annulus, a key cardiac structure, exhibits regional stability differences. Its septal region is most stable, while posterior and lateral regions are more vulnerable to injury and shape changes.
Area of Science:
- Cardiac Anatomy
- Histology
- Cardiovascular Research
Background:
- The term annulus fibrosus is clinically used but lacks formal anatomical nomenclature.
- This structure is implicated as a substrate for cardiac excitation propagation.
- Cardiac damage from blunt chest trauma, though rare, often involves the right fibrous annulus.
Purpose of the Study:
- To histologically examine the fibrous annulus, specifically the right fibrous annulus.
- To determine the stability and heterogeneity of different regions of the fibrous annulus.
- To investigate the potential role of the fibrous annulus in the dynamic changes of the right atrio-ventricular ostium.
Main Methods:
- Histological examination of cardiac tissue.
- Macroscopic analysis (referenced from previous study).
- Comparative analysis of regional stability within the fibrous annulus.
Main Results:
- Histological findings corroborate previous macroscopic observations.
- The septal part and anterior angle of the right ventricle represent the most stable regions of the fibrous annulus.
- The lateral and posterior angles, along with the posterior part of the right ventricle, are the most labile regions.
Conclusions:
- The right fibrous annulus is a structurally heterogeneous entity.
- Regional differences in stability may influence susceptibility to injury.
- The fibrous annulus likely contributes to alterations in the right atrio-ventricular ostium shape throughout life.
