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Updated: Jun 23, 2026

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Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment
Published on: April 4, 2017
Biosensing by densely packed and optically coupled plasmonic particle arrays.
Takumi Sannomiya1, Pratap K Sahoo, Davut I Mahcicek
1Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, ETH Zurich, Gloriastrasse 35, 8092 Zurich, Switzerland.
Small (Weinheim an Der Bergstrasse, Germany)
|April 23, 2009
Summary
Densely packed plasmonic particle arrays show promise for biosensing. These arrays enhance sensitivity for detecting low analyte concentrations, with potential for detecting streptavidin below 150 pM.
Area of Science:
- Plasmonics
- Nanotechnology
- Biosensing
Background:
- Densely packed plasmonic particle arrays exhibit interparticle optical coupling.
- This coupling creates a strong localized field beneficial for sensing applications.
Purpose of the Study:
- To investigate the biosensing capabilities of densely packed plasmonic particle arrays.
- To analyze sensor properties including bulk sensitivity, layer sensitivity, and sensitivity depth.
- To examine sensitivity to low analyte concentrations using dynamic adsorption processes.
Main Methods:
- Utilized a multiple multipole program to model and analyze sensor properties.
- Simulated dynamic adsorption processes to assess sensitivity to low concentrations.
Main Results:
- The study characterized bulk sensitivity, layer sensitivity, and sensitivity depth of the plasmonic arrays.
- Investigated the dynamic adsorption of analytes to understand low-concentration detection.
Conclusions:
- Plasmonic particle arrays offer a promising platform for sensitive biosensing.
- The system is expected to detect streptavidin at concentrations below 150 pM within 3000 seconds based on signal-to-noise ratios.

