Related Experiment Video
Updated: Jun 23, 2026

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
Published on: July 2, 2021
The correlation between minor or unrecognized developmental deformities and the development of osteoarthritis of the
1Department of Orthopaedic Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
Abstract:
The 20th century brought three major conceptual changes about osteoarthritis of the hip. The first was a dramatic change in the understanding of the etiology of many cases of osteoarthritis of the hip. The second was the establishment of the mechanism by which minor developmental abnormalities lead to arthritis. The third was, for the first time, the possibility that the rate of disease development could be retarded and even possibly prevented from progressing. To understand these conceptual changes, it is essential to define the terms used to describe osteoarthritis of the hip.
Related Concept Videos
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Ankle Joint
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
