Related Experiment Video
Updated: Jun 23, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Osteoporosis: management and densitometry for orthopaedic surgeons
Laura M B Gehrig1, Cory Collinge, John Kaufman
1Department of General Orthopaedics, Metabolic Bone Disease, Densitometry, Osteoporosis, Shreveport, Louisiana, USA.
Abstract:
Osteoporosis is a metabolic condition that is increasing in prevalence as people live longer. A fracture is a sentinel event. Despite all the advances in technology, a history of low-energy fracture in adulthood is the best predictor of future fracture-an even better predictor than low bone mineral density. Osteoporosis and the risk of fracture go hand in hand. The orthopaedic surgeon is often viewed as an expert in managing and treating bone disorders. Given that the orthopaedic surgeon is often the first and only physician to evaluate a patient with a fracture, he or she may be in the ideal position to initiate patient evaluation and therapy. However, many times the orthopaedic surgeon is concerned about the adverse effects of the pharmacologic treatment of osteoporosis to the extent that prescribing these drugs is avoided. A treatment approach incorporating nonpharmacologic agents is an effective strategy in the prevention and treatment of osteoporosis.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Osteoclasts in Bone Remodeling
Bone Remodeling
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Remodeling and Repair
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
