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Inter-helical interactions in membrane proteins: analysis based on the local backbone geometry and the side chain

Anupam Nath Jha1, Saraswathi Vishveshwara

  • 1Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.

Journal of Biomolecular Structure & Dynamics
|April 24, 2009
PubMed
Summary

This study quantitatively analyzes helix-helix packing in alpha-helical membrane proteins. A single parameter, alpha, accurately describes interactions, revealing preferences in anti-parallel and parallel helix arrangements.

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