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Estimating the probability of stroke in Korean hypertensive patients visiting tertiary hospitals using a risk profile
Cheol Ung Choi1, Chang Gyu Park
1Cardiovascular Center, Korea University Guro Hospital, Seoul, Korea. wmagpie@korea.com
Insights
Hypertension significantly increases stroke risk in Korean patients, with an average 10-year probability of 24.27%. Aggressive blood pressure management is crucial for stroke prevention in this population.
Area of Science:
- Cardiology
- Neurology
- Public Health
Background:
- Hypertension is a primary modifiable risk factor for stroke.
- Understanding stroke risk factors and probabilities in hypertensive populations is critical for public health initiatives.
Purpose of the Study:
- To investigate the distribution of stroke risk factors.
- To determine the 10-year probability of stroke in Korean hypertensive patients.
Main Methods:
- 1,402 hypertensive patients from 37 hospitals were enrolled.
- Stroke risk factors were assessed via laboratory tests and physical examinations.
- The Framingham stroke risk equation was used to calculate the 10-year stroke probability.
Main Results:
- 37.2% of patients had uncontrolled hypertension despite treatment.
- The average 10-year stroke probability was 24.27%, 2.4 times higher than the KCPS cohort.
- Stroke probability increased with age and blood pressure levels.
Conclusions:
- High stroke risk in hypertensive patients necessitates aggressive interventions.
- Reducing blood pressure is essential for mitigating stroke risk.
- Targeted interventions are needed for Korean hypertensive patients.
Background:
Hypertension is the most important single modifiable risk factor for stroke. We investigated the distribution of stroke risk factors and 10-year probability of stroke in Korean hypertensive patients.
Methods:
A total of 1,402 hypertensive patients treated by cardiology departments at 37 general hospitals nationwide were enrolled. Risk factors for stroke were evaluated using a series of laboratory tests and physical examinations, and the 10-year probability of stroke was determined by applying the Framingham stroke risk equation.
Results:
The proportion of patients who have uncontrolled hypertension despite use of antihypertensives was 37.2% (37.2% women, 37.3% men, p = 0.990). The average 10-year probability of stroke in hypertensive patients was 24.27% (24.17% women, 24.39% men, p = 0.825), approximately 2.4 times higher than of the risk of stroke observed in the Korean Cancer Prevention Study [KCPS] cohort. The 10-year stroke probability in patients with hypertension increased in proportion to age. In patients for hypertension, the 10-year probability of stroke increased in proportion to blood pressure.
Conclusion:
Aggressive interventions are mandated to reduce blood pressure and alleviate the high risk of stroke in hypertensive patients.
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