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Related Experiment Video

Updated: Jun 23, 2026

Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
06:23

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Published on: August 4, 2018

Prophylactic argon plasma coagulation ablation does not decrease delayed postpolypectomy bleeding.

Chang Kyun Lee1, Suck-Ho Lee, Ji-Young Park

  • 1Division of Gastroenterology, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Republic of Korea.

Gastrointestinal Endoscopy
|April 24, 2009
PubMed
Summary
This summary is machine-generated.

Prophylactic argon plasma coagulation (APC) did not significantly reduce delayed postpolypectomy bleeding (PPB) after colonoscopic polypectomy. This study found no added benefit of APC in preventing this common complication.

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Area of Science:

  • Gastroenterology
  • Endoscopic Procedures
  • Surgical Complications

Background:

  • Postpolypectomy bleeding (PPB) is a common complication following colonoscopic polypectomy.
  • Delayed PPB, occurring days after the procedure, lacks established preventive guidelines.
  • Submucosal vessels within the artificial ulcer may contribute to delayed bleeding.

Purpose of the Study:

  • To evaluate the efficacy of prophylactic argon plasma coagulation (APC) in preventing delayed PPB.
  • To assess if coagulating nonbleeding visible vessels reduces the incidence of delayed bleeding after polypectomy.

Main Methods:

  • A prospective, randomized, controlled study was conducted at a tertiary referral center.
  • 987 polyps were resected from 600 patients undergoing colonoscopic polypectomy.
  • The intervention group received APC for nonbleeding visible vessels; the control group did not.

Main Results:

  • Delayed PPB occurred in 3.3% of all patients (2.5% APC group vs. 4.3% control group).
  • No statistically significant difference in delayed PPB rates was observed between the APC and control groups.
  • No significant APC-related complications were reported.

Conclusions:

  • Prophylactic APC ablation of nonbleeding visible vessels does not offer an advantage in preventing delayed PPB.
  • Current findings suggest that APC may not be beneficial for preventing delayed bleeding after colonoscopic polypectomy.