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Updated: Jun 23, 2026

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Published on: May 19, 2022
"It's not like I can change my mind later": reversibility and decision timing in prostate cancer treatment
Nora B Henrikson1, William J Ellis, Donna L Berry
1University of Washington School of Public Health and Community Medicine, Institute for Public Health Genetics, Seattle, WA 98195, USA. nhenriks@u.washington.edu
Objective:
To explore whether reversibility, decision timing, and uncertainty are relevant to men deciding on treatment for localized prostate cancer (LPC).
Design:
Secondary qualitative data analysis of unstructured interviews.
Methods:
Content analysis of previously collected qualitative data (31 individual interviews, 5 focus groups). We identified the frequency of references to reversibility, decision timing, and uncertainty and related sub-themes.
Results:
We identified eight themes: reversibility, timing of decision, number of options, "getting it over with," "the way I make decisions," uncertainty among experts, desire for certainty, and probability. Fifteen men mentioned reversibility in individual interviews; 13 mentioned the importance of the timing of their decision. Eleven mentioned the importance of the number of options; twelve "the way I make decisions." Eleven men mentioned the uncertainty of experts, fourteen the desire to "get it over with," and six a desire for certainty.
Conclusion:
This study provides compelling preliminary data suggesting that men consider the reversibility, decision timing, and uncertainty in the prostate cancer treatment decision.
Practice Implication:
These findings may be helpful in enhancing support for men facing the treatment decision.
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